A prospective <scp>STudy</scp> using <scp>invAsive</scp> haemodynamic measurements <scp>foLLowing</scp> catheter ablation for <scp>AF</scp> and early <scp>HFpEF</scp> : <scp>STALL AF?HFpEF</scp>

Aims The impact of atrial fibrillation (AF) ablation in early heart failure with preserved ejection fraction (HFpEF) is unknown. Our aim was to determine the AF on symptoms and exercise haemodynamic parameters HFpEF. Methods results Symptomatic patients referred for index ?50% underwent baseline quality life questionnaires, echocardiography, cardiac magnetic resonance imaging, right catheterisation (exRHC), brain natriuretic peptide (BNP) testing. HFpEF defined by resting pulmonary capillary wedge pressure (PCWP) ?15 mmHg or peak PCWP ?25 mmHg. Patients were offered follow-up exRHC ?6 months post-ablation. Of 54 undergoing evaluation, 35 (65%) had identified exRHC. older (64 ± 10 vs. 13 years, P < 0.01), more frequently female (54% 16%, hypertensive (63% 0.001), suffering persistent (66% 11%, compared those without Twenty 12 6 Nine (45%) no longer fulfilled criteria at follow-up. remaining arrhythmia free (n = 9, 45%) showed significant improvements (29 4 23 2 mmHg, 0.01) Minnesota Living Heart Failure (MLHF) score (55 30 22 30, while remainder did not (PCWP 31 5 30.0 NS; MLHF 55 25 20, NS). Conclusion coexists symptomatic fraction. Restoration maintenance sinus rhythm comorbid improves parameters, BNP associated